Перегляд за автором "Tkachuk, Z.Yu."

Результати 1-3 з 3

2'-5'-Oligoadenylates as a «tool» of innate immunity

Tkachuk, Z.Yu. (Вiopolymers and Cell, 2013)

It is a matter of common knowledge, that «core» 2'-5'-oligoadenylates and their analogues posses broader biological activity than it can be predicted within the traditional «interferon» hypothesis. They exhibit immunomodulatory ...
Studies on interaction of oligoadenylates with proteins in vitro by MALDI-TOF mass spectrometry

Levchenko, S.M.; Rebriev, A.V.; Tkachuk, V.V.; Dubey, L.V.; Dubey, I.Ya.; Tkachuk, Z.Yu. (Вiopolymers and Cell, 2013)

Aim. To investigate the ability of «core» 2'-5'- and 3'-5'-oligoadenylates (OA) to interact with α-interferon – a key protein of the 2'- 5'-OAS/RNAase L system responsible for antiviral cell defense. Methods. MALDI-TOF ...
Study of dephosphorylated 2'-5'-linked oligoadenylates impact on apo-S100A1 protein conformation by heteronuclear NMR and circular dichroism

Skorobogatov, O.Yu.; Lozhko, D.N.; Zhukov, I.Yu.; Kozlov, O.V.; Tkachuk, Z.Yu. (Вiopolymers and Cell, 2014)

Low molecular weight natural mediators, 2'-5'-linked oligoadenylates, play an important role in interferon-based antiviral mechanism; participate in growth, apoptosis and other important cellular processes. The aim of ...

Результати 1-3 з 3

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